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Distinct Modulatory Effects of Satiety and Sibutramine on Brain Responses to Food Images in Humans: A Double Dissociation across Hypothalamus, Amygdala, and Ventral Striatum

We used functional magnetic resonance imaging to explore brain responses to food images in overweight humans, examining independently the impact of a prescan meal (“satiety”) and the anti-obesity drug sibutramine, a serotonin and noradrenaline reuptake inhibitor. We identified significantly differen...

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Detalhes bibliográficos
Main Authors: Fletcher, Paul C., Napolitano, Antonella, Skeggs, Andrew, Miller, Sam R., Delafont, Bruno, Cambridge, Victoria C., de Wit, Sanne, Nathan, Pradeep J., Brooke, Allison, O'Rahilly, Stephen, Farooqi, I. Sadaf, Bullmore, Edward T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447260/
https://ncbi.nlm.nih.gov/pubmed/20980590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3323-10.2010
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