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Immunoglobulin gene rearrangement as a diagnostic criterion of B-cell lymphoma.

We describe the use of the Southern blot hybridization technique to diagnose B-cell lymphoma by detecting clonal immunoglobulin gene rearrangements in lymph node and other biopsy tissues. DNA was isolated from a wide variety of neoplastic and non-neoplastic specimens and analyzed for the presence of...

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Détails bibliographiques
Auteurs principaux: Cleary, M L, Chao, J, Warnke, R, Sklar, J
Format: Artigo
Langue:Inglês
Publié: 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC344725/
https://ncbi.nlm.nih.gov/pubmed/6607475
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