Less than 5 Netrin-1 molecules initiate attraction but 200 Sema3A molecules are necessary for repulsion

Guidance molecules, such as Sema3A or Netrin-1, induce growth cone (GC) repulsion or attraction. In order to determine the speed of action and efficiency of these guidance cues we developed an experimental procedure to deliver controlled amounts of these molecules. Lipid vesicles encapsulating 10–10...

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Hlavní autoři: Pinato, Giulietta, Cojoc, Dan, Lien, Linh Thuy, Ansuini, Alessio, Ban, Jelena, D’Este, Elisa, Torre, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447186/
https://ncbi.nlm.nih.gov/pubmed/22997549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00675
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