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Neutron-capture therapy of human cancer: in vivo results on tumor localization of boron-10-labeled antibodies to carcinoembryonic antigen in the GW-39 tumor model system.

Antibody against carcinoembryonic antigen (CEA) was conjugated with p-[1,2-dicarba-closo-[1-3H]do-decaboran(12)-2-yl] benzenediazonium ion by an azo-coupling reaction, resulting in 30 boron atoms per IgG molecule with no loss of antibody protein. Antibody immunoreactivity was not appreciably affecte...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Goldenberg, D M, Sharkey, R M, Primus, F J, Mizusawa, E, Hawthorne, M F
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344718/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6582510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.2.560
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