Rapid release of galactose-terminated ligands after endocytosis by hepatic parenchymal cells: evidence for a role of carbohydrate structure in the release of internalized ligand from receptor.

We have compared the behavior of 125I-labeled asialoorosomucoid (ASOR) and 125I-labeled asialotriantennary glycopeptide (TRI) from alpha-1-protease inhibitor in the perfused rat liver. These two ligands are recognized and internalized by the Gal/GalNAc receptor system of hepatocytes. We found that b...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Townsend, R R, Wall, D A, Hubbard, A L, Lee, Y C
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1984
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6320189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.2.466
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