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Dynamics of enzymatic reactions.

The detailed molecular dynamics of an actual bond-breaking event in a fluctuating enzyme substrate complex is simulated. The method developed allows one to explore what type of fluctuations are involved in enzymatic reactions and to evaluate entropic contributions to enzyme catalysis. The fluctuatio...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Hovedforfatter: Warshel, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6582500/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.2.444
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