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Cardiopulmonary Bypass during Cardiac Surgery Modulates Systemic Inflammation by Affecting Different Steps of the Leukocyte Recruitment Cascade

BACKGROUND: It is known that the use of a cardiopulmonary bypass (CPB) during cardiac surgery leads to leukocyte activation and may, among other causes, induce organ dysfunction due to increased leukocyte recruitment into different organs. Leukocyte extravasation occurs in a cascade-like fashion, in...

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Bibliografiske detaljer
Main Authors: Rossaint, Jan, Berger, Christian, Van Aken, Hugo, Scheld, Hans H., Zahn, Peter K., Rukosujew, Andreas, Zarbock, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446926/
https://ncbi.nlm.nih.gov/pubmed/23029213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045738
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