A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity

Drug/radiation resistance to treatment and tumor relapse are major obstacles in identifying a cure for cancer. Development of novel agents that address these challenges would therefore be of the upmost importance in the fight against cancer. In this regard, studies show that the antiapoptotic protei...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ling, Xiang, Cao, Shousong, Cheng, Qiuying, Keefe, James T., Rustum, Youcef M., Li, Fengzhi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446924/
https://ncbi.nlm.nih.gov/pubmed/23029106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045571
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