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Coinhibitory Molecules in Autoimmune Diseases
Coinhibitory molecules such as CTLA-4, PD-1 and BTLA negatively regulate immune responses. Multiple studies indicate that the deficiency or mutation of coinhibitory molecules leads to the development of autoimmune diseases in mice and humans, indicating that the negative signals from coinhibitory mo...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Hindawi Publishing Corporation
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3446788/ https://ncbi.nlm.nih.gov/pubmed/22997525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/269756 |
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