Ionizing radiation and tritium transmutation both cause formation of 5-hydroxymethyl-2'-deoxyuridine in cellular DNA.

HeLa cells grown in the presence of [methyl-3H]thymidine contained large amounts of 5-hydroxymethyl-2'-deoxyuridine (HMdU) in their DNA. When the cells were grown in [6-3H]thymidine and their DNA was labeled to the same specific activity, no HMdU was present. When such [6-3H]thymidine-labeled cells...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Teebor, G W, Frenkel, K, Goldstein, M S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6582490/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.2.318
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