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Nectin4 Is an Epithelial Cell Receptor for Canine Distemper Virus and Involved in Neurovirulence

Canine distemper virus (CDV) uses signaling lymphocyte activation molecule (SLAM), expressed on immune cells, as a receptor. However, epithelial and neural cells are also affected by CDV in vivo. Wild-type CDV strains showed efficient replication with syncytia in Vero cells expressing dog nectin4, a...

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Detalhes bibliográficos
Main Authors: Pratakpiriya, Watanyoo, Seki, Fumio, Otsuki, Noriyuki, Sakai, Kouji, Fukuhara, Hideo, Katamoto, Hiromu, Hirai, Takuya, Maenaka, Katsumi, Techangamsuwan, Somporn, Lan, Nguyen Thi, Takeda, Makoto, Yamaguchi, Ryoji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446623/
https://ncbi.nlm.nih.gov/pubmed/22761370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00824-12
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