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Virion-Associated Complement Regulator CD55 Is More Potent than CD46 in Mediating Resistance of Mumps Virus and Vesicular Stomatitis Virus to Neutralization

Enveloped viruses can incorporate host cell membrane proteins during the budding process. Here we demonstrate that mumps virus (MuV) and vesicular stomatitis virus (VSV) assemble to include CD46 and CD55, two host cell regulators which inhibit propagation of complement pathways through distinct mech...

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Detalhes bibliográficos
Main Authors: Johnson, John B., Lyles, Douglas S., Alexander-Miller, Martha A., Parks, Griffith D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446622/
https://ncbi.nlm.nih.gov/pubmed/22761385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01154-12
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