Restricted Varicella-Zoster Virus Transcription in Human Trigeminal Ganglia Obtained Soon after Death

We analyzed the varicella-zoster virus (VZV) transcriptome in 43 latently infected human trigeminal ganglia (TG) with postmortem intervals (PMIs) ranging from 3.7 to 24 h. Multiplex reverse transcriptase PCR (RT-PCR) revealed no VZV transcripts with a PMI of <9 h. Real-time PCR indicated a signif...

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Main Authors: Ouwendijk, Werner J. D., Choe, Alexander, Nagel, Maria A., Gilden, Don, Osterhaus, Albert D. M. E., Cohrs, Randall J., Verjans, Georges M. G. M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
主題:
Genome Replication and Regulation of Viral Gene Expression
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446590/
https://ncbi.nlm.nih.gov/pubmed/22740396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01331-12
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