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Vaccination with Adenovirus Serotypes 35, 26, and 48 Elicits Higher Levels of Innate Cytokine Responses than Adenovirus Serotype 5 in Rhesus Monkeys

Adenovirus (Ad) vaccine vectors have proven highly immunogenic in multiple experimental models, but the innate immune responses induced by these vectors remain poorly characterized. Here we report innate cytokine responses to 5 different Ad vectors in 26 rhesus monkeys. Vaccination with adenovirus s...

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Bibliographic Details
Main Authors: Teigler, Jeffrey E., Iampietro, M. Justin, Barouch, Dan H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446581/
https://ncbi.nlm.nih.gov/pubmed/22787208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00740-12
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