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The C11R Gene, Which Encodes the Vaccinia Virus Growth Factor, Is Partially Responsible for MVA-Induced NF-κB and ERK2 Activation

MVA is an attenuated strain of vaccinia virus (VACV) that is a popular vaccine vector. MVA infection activates NF-κB. For 293T cells, it is known that MVA early gene expression activates extracellular signal-regulated kinase 2 (ERK2), resulting in NF-κB activation. However, other viral and cellular...

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Detalhes bibliográficos
Main Authors: Martin, Stefani, Harris, Daniel T., Shisler, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446577/
https://ncbi.nlm.nih.gov/pubmed/22740414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06279-11
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