Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81

Hepatitis C virus (HCV) causes chronic liver disease, cirrhosis, and primary liver cancer. Despite 130 million people being at risk worldwide, no vaccine exists, and effective therapy is limited by drug resistance, toxicity, and high costs. The tetraspanin CD81 is an essential entry-level receptor r...

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Bibliografiska uppgifter
Huvudupphovsmän: Rajesh, Sundaresan, Sridhar, Pooja, Tews, Birke Andrea, Fénéant, Lucie, Cocquerel, Laurence, Ward, Douglas G., Berditchevski, Fedor, Overduin, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Structure and Assembly
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446547/
https://ncbi.nlm.nih.gov/pubmed/22740401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00559-12
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