Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81

Hepatitis C virus (HCV) causes chronic liver disease, cirrhosis, and primary liver cancer. Despite 130 million people being at risk worldwide, no vaccine exists, and effective therapy is limited by drug resistance, toxicity, and high costs. The tetraspanin CD81 is an essential entry-level receptor r...

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Detalhes bibliográficos
Main Authors: Rajesh, Sundaresan, Sridhar, Pooja, Tews, Birke Andrea, Fénéant, Lucie, Cocquerel, Laurence, Ward, Douglas G., Berditchevski, Fedor, Overduin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446547/
https://ncbi.nlm.nih.gov/pubmed/22740401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00559-12
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