Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81

Hepatitis C virus (HCV) causes chronic liver disease, cirrhosis, and primary liver cancer. Despite 130 million people being at risk worldwide, no vaccine exists, and effective therapy is limited by drug resistance, toxicity, and high costs. The tetraspanin CD81 is an essential entry-level receptor r...

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Библиографические подробности
Главные авторы: Rajesh, Sundaresan, Sridhar, Pooja, Tews, Birke Andrea, Fénéant, Lucie, Cocquerel, Laurence, Ward, Douglas G., Berditchevski, Fedor, Overduin, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
Предметы:
Structure and Assembly
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446547/
https://ncbi.nlm.nih.gov/pubmed/22740401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00559-12
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