Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81

Hepatitis C virus (HCV) causes chronic liver disease, cirrhosis, and primary liver cancer. Despite 130 million people being at risk worldwide, no vaccine exists, and effective therapy is limited by drug resistance, toxicity, and high costs. The tetraspanin CD81 is an essential entry-level receptor r...

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Autores principales: Rajesh, Sundaresan, Sridhar, Pooja, Tews, Birke Andrea, Fénéant, Lucie, Cocquerel, Laurence, Ward, Douglas G., Berditchevski, Fedor, Overduin, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Structure and Assembly
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446547/
https://ncbi.nlm.nih.gov/pubmed/22740401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00559-12
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