Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity

INTRODUCTION: CD200 is a type I transmembrane glycoprotein that can regulate the activation threshold of inflammatory immune responses, polarize cytokine production, and maintain immune homeostasis. We therefore evaluated the functional status of CD200/CD200 receptor 1 (CD200R1) interactions in subj...

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Hlavní autoři: Li, Yang, Zhao, Li-dan, Tong, Lu-sha, Qian, Su-ning, Ren, Yan, Zhang, Lei, Ding, Xin, Chen, Yang, Wang, Yan-xia, Zhang, Wen, Zeng, Xiao-feng, Zhang, Feng-chun, Tang, Fu-lin, Zhang, Xuan, Ba, De-nian, He, Wei, Cao, Xue-tao, Lipsky, Peter E
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446504/
https://ncbi.nlm.nih.gov/pubmed/22621248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3853
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