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Inhibition of malignant transformation in vitro by inhibitors of poly(ADP-ribose) synthesis.

Malignant transformation in vitro of hamster embryo cells and mouse C3H 10T 1/2 cells by x-rays, ultraviolet light, and chemical carcinogens was inhibited by benzamide and by 3-aminobenzamide at concentrations that are specific for inhibition of poly(ADP-ribose) formation. These compounds slow the l...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Borek, C, Morgan, W F, Ong, A, Cleaver, J E
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1984
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6582479/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.1.243
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