The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study

INTRODUCTION: The aim of this study was to investigate the effect of three years of tumor necrosis factor-alpha (TNF-α) blocking therapy on bone turnover as well as to analyze the predictive value of early changes in bone turnover markers (BTM) for treatment discontinuation in patients with ankylosi...

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Detalhes bibliográficos
Main Authors: Arends, Suzanne, Spoorenberg, Anneke, Houtman, Pieternella M, Leijsma, Martha K, Bos, Reinhard, Kallenberg, Cees GM, Groen, Henk, Brouwer, Elisabeth, van der Veer, Eveline
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446472/
https://ncbi.nlm.nih.gov/pubmed/22546520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3823
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