Smoking interacts with HLA-DRB1 shared epitope in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis: results from the Malaysian Epidemiological Investigation of Rheumatoid Arthritis (MyEIRA)

INTRODUCTION: Rheumatoid arthritis (RA) is a multifactorial autoimmune disease in which genetic and environmental factors interact in the etiology. In this study, we investigated whether smoking and HLA-DRB1 shared-epitope (SE) alleles interact differently in the development of the two major subgrou...

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Détails bibliographiques
Auteurs principaux: Too, Chun Lai, Yahya, Abqariyah, Murad, Shahnaz, Dhaliwal, Jasbir Singh, Larsson, Per Tobias, Muhamad, Nor Asiah, Abdullah, Nor Aini, Mustafa, Amal Nasir, Klareskog, Lars, Alfredsson, Lars, Padyukov, Leonid, Bengtsson, Camilla
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446463/
https://ncbi.nlm.nih.gov/pubmed/22537824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3813
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