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Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan

INTRODUCTION: The neuron-glial antigen 2 (NG2) proteoglycan promotes pericyte recruitment and mediates pericyte interaction with endothelial cells. In the absence of NG2, blood vessel development is negatively impacted in several pathological models. Our goal in this study was to determine the effec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gibby, Krissa, You, Weon-Kyoo, Kadoya, Kuniko, Helgadottir, Hildur, Young, Lawrence JT, Ellies, Lesley G, Chang, Yunchao, Cardiff, Robert D, Stallcup, William B
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446402/
https://ncbi.nlm.nih.gov/pubmed/22531600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3174
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