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Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan

INTRODUCTION: The neuron-glial antigen 2 (NG2) proteoglycan promotes pericyte recruitment and mediates pericyte interaction with endothelial cells. In the absence of NG2, blood vessel development is negatively impacted in several pathological models. Our goal in this study was to determine the effec...

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Detalhes bibliográficos
Main Authors: Gibby, Krissa, You, Weon-Kyoo, Kadoya, Kuniko, Helgadottir, Hildur, Young, Lawrence JT, Ellies, Lesley G, Chang, Yunchao, Cardiff, Robert D, Stallcup, William B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446402/
https://ncbi.nlm.nih.gov/pubmed/22531600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3174
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