Paracrine interactions between primary human macrophages and human fibroblasts enhance murine mammary gland humanization in vivo

INTRODUCTION: Macrophages comprise an essential component of the mammary microenvironment necessary for normal gland development. However, there is no viable in vivo model to study their role in normal human breast function. We hypothesized that adding primary human macrophages to the murine mammary...

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Main Authors: Fleming, Jodie M, Miller, Tyler C, Kidacki, Michal, Ginsburg, Erika, Stuelten, Christina H, Stewart, Delisha A, Troester, Melissa A, Vonderhaar, Barbara K
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446360/
https://ncbi.nlm.nih.gov/pubmed/22731827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3215
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