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MEK inhibition suppresses cell invasion and migration in ovarian cancers with activation of ERK1/2

The extracellular-regulated kinase (ERK) signaling pathway plays an important role in regulating the malignant potential of a cancer cell. However, the effect of ERK signaling on cancer metastasis is not clearly understood. In the present study, we examined the status of ERK activation in 88 ovarian...

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Bibliographische Detailangaben
Hauptverfasser: KATAGIRI, ATSUKO, NAKAYAMA, KENTARO, RAHMAN, MOHAMMED TANJIMUR, RAHMAN, MUNMUN, YEASMIN, SHAMIMA, ISHIKAWA, MASAKO, IIDA, KOUJI, NAKAYAMA, NAOMI, MIYAZAKI, KHOJI
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445873/
https://ncbi.nlm.nih.gov/pubmed/22993581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm_00000093
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