Step-Wise Assembly, Maturation and Dynamic Behavior of the Human CENP-P/O/R/Q/U Kinetochore Sub-Complex

Kinetochores are multi-protein megadalton assemblies that are required for attachment of microtubules to centromeres and, in turn, the segregation of chromosomes in mitosis. Kinetochore assembly is a cell cycle regulated multi-step process. The initial step occurs during interphase and involves load...

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Autores principales: Eskat, Anja, Deng, Wen, Hofmeister, Antje, Rudolphi, Sven, Emmerth, Stephan, Hellwig, Daniela, Ulbricht, Tobias, Döring, Volker, Bancroft, James M., McAinsh, Andrew D., Cardoso, M. Cristina, Meraldi, Patrick, Hoischen, Christian, Leonhardt, Heinrich, Diekmann, Stephan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445539/
https://ncbi.nlm.nih.gov/pubmed/23028590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044717
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