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Modulation of Invasive Phenotype by Interstitial Pressure-Driven Convection in Aggregates of Human Breast Cancer Cells

This paper reports the effect of elevated pressure on the invasive phenotype of patterned three-dimensional (3D) aggregates of MDA-MB-231 human breast cancer cells. We found that the directionality of the interstitial pressure profile altered the frequency of invasion by cells located at the surface...

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Detalhes bibliográficos
Main Authors: Tien, Joe, Truslow, James G., Nelson, Celeste M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445465/
https://ncbi.nlm.nih.gov/pubmed/23028839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045191
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