The Aryl Hydrocarbon Receptor Influences Transplant Outcomes in Response to Environmental Signals

The aryl hydrocarbon receptor (AHR) is a cytosolic transcription factor with numerous endogenous and xenobiotic ligands, most notably 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Recent data suggests that TCDD may induce regulatory T cells, while a second AHR ligand, FICZ, promotes Th17 differentiati...

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Bibliographic Details
Main Authors: Pauly, S. Kyle, Fechner, John H., Zhang, Xiaoji, Torrealba, Jose, Bradfield, Christopher A., Mezrich, Joshua D.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445427/
https://ncbi.nlm.nih.gov/pubmed/23002321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02772248.2012.688546
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