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GPU Accelerated Chemical Similarity Calculation for Compound Library Comparison

Chemical similarity calculation plays an important role in compound library design, virtual screening, and “lead” optimization. In this manuscript, we present a novel GPU-accelerated algorithm for all-vs-all Tanimoto matrix calculation and nearest neighbor search. By taking advantage of multi-core G...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ma, Chao, Wang, Lirong, Xie, Xiang-Qun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445263/
https://ncbi.nlm.nih.gov/pubmed/21692447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci1004948
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