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Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects
Frontotemporal lobar degeneration (FTLD) is clinically, pathologically and genetically heterogeneous. Three major proteins are implicated in its pathogenesis. About half of cases are characterized by depositions of the microtubule associated protein, tau (FTLD-tau). In most of the remaining cases, d...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445027/ https://ncbi.nlm.nih.gov/pubmed/22878865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1030-4 |
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