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Traumatic Noise Activates Rho-Family GTPases through Transient Cellular Energy Depletion

Small GTPases mediate transmembrane signaling and regulate the actin cytoskeleton in eukaryotic cells. Here, we characterize the auditory pathology of adult male CBA/J mice exposed to traumatic noise (2–20 kHz; 106 dB; 2 h). Loss of outer hair cells was evident 1 h after noise exposure in the basal...

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Detalhes bibliográficos
Main Authors: Chen, Fu-Quan, Zheng, Hong-Wei, Hill, Kayla, Sha, Su-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445016/
https://ncbi.nlm.nih.gov/pubmed/22956833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6381-11.2012
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