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Traumatic Noise Activates Rho-Family GTPases through Transient Cellular Energy Depletion
Small GTPases mediate transmembrane signaling and regulate the actin cytoskeleton in eukaryotic cells. Here, we characterize the auditory pathology of adult male CBA/J mice exposed to traumatic noise (2–20 kHz; 106 dB; 2 h). Loss of outer hair cells was evident 1 h after noise exposure in the basal...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society for Neuroscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445016/ https://ncbi.nlm.nih.gov/pubmed/22956833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6381-11.2012 |
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