Rapid T cell repopulation after rabbit anti-thymocyte globulin (rATG) treatment is driven mainly by cytomegalovirus

Rabbit anti-thymocyte globulin (rATG) induces a long-lasting lymphocytopenia. CD4(+) T cells remain depleted for up to 2 years, whereas the CD8(+) T cell compartment is refilled rapidly by highly differentiated CD27(-)CD45RA(+)CD57(+)effector-type cells. Because the presence of these highly differen...

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Autores principales: Havenith, S H C, Remmerswaal, E B M, Bemelman, F J, Yong, S L, van Donselaar- van der Pant, K A M I, van Lier, R A W, ten Berge, I J M
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2012
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445006/
https://ncbi.nlm.nih.gov/pubmed/22861369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04622.x
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