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Sclerostin Antibody Increases Bone Volume and Enhances Implant Fixation in a Rat Model

BACKGROUND: Previous studies have demonstrated that sclerostin blockade is anabolic for bone. This study examined whether systemic administration of sclerostin antibody would increase implant fixation and peri-implant bone volume in a rat model. METHODS: Titanium cylinders were placed in the femoral...

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Bibliographic Details
Main Authors: Virdi, Amarjit S., Liu, Min, Sena, Kotaro, Maletich, James, McNulty, Margaret, Ke, Hua Zhu, Sumner, Dale R.
Format: Artigo
Language:Inglês
Published: Journal of Bone and Joint Surgery, Inc. 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444952/
https://ncbi.nlm.nih.gov/pubmed/22992878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.K.00344
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