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A shot in the genome: how accurately do shotgun 454 sequences represent a genome?

BACKGROUND: Next generation sequencing (NGS) provides a valuable method to quickly obtain sequence information from non-model organisms at a genomic scale. In principle, if sequencing is not targeted for a genomic region or sequence type (e.g. coding region, microsatellites) NGS reads can be used as...

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Detalhes bibliográficos
Main Authors: Meglécz, Emese, Pech, Nicolas, Gilles, André, Martin, Jean-François, Gardner, Michael G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444912/
https://ncbi.nlm.nih.gov/pubmed/22640415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-259
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