Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1

Nitric oxide (NO) defends against intracellular pathogens but its synthesis must be regulated due to cell and tissue toxicity. During infection, macrophages import extracellular arginine to synthesize NO, generating the byproduct citrulline. Accumulated intracellular citrulline is thought to fuel ar...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Qualls, Joseph E., Subramanian, Chitra, Rafi, Wasiulla, Smith, Amber M., Balouzian, Liza, DeFreitas, Ashley A., Shirey, Kari Ann, Reutterer, Benjamin, Kernbauer, Elisabeth, Stockinger, Silvia, Decker, Thomas, Miyairi, Isao, Vogel, Stefanie N., Salgame, Padmini, Rock, Charles O., Murray, Peter J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444824/
https://ncbi.nlm.nih.gov/pubmed/22980328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.07.012
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller