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Phase 1–2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer

BACKGROUND: Biologically targeted therapies have been postulated as a viable strategy to improve outcomes for women with ovarian cancer. We assessed the safety, tolerance, pharmacokinetics, relevant circulating and image-derived biomarkers, and clinical activity of combination aflibercept and doceta...

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Detalhes bibliográficos
Main Authors: Coleman, Robert L, Duska, Linda R, Ramirez, Pedro T, Heymach, John V, Kamat, Aparna A, Modesitt, Susan C, Schmeler, Kathleen M, Iyer, Revathy B, Garcia, Michael E, Millera, Debbie L, Jackson, Edward F, Ng, Chaan S, Kundra, Vikas, Jaffe, Robert, Sood, Anil K
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444811/
https://ncbi.nlm.nih.gov/pubmed/21992853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(11)70244-3
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