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INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells

T cell antigen receptor–proximal signaling components, Rho-family GTPases, and formin proteins DIA1 and FMNL1 have been implicated in centrosome reorientation to the immunological synapse of T lymphocytes. However, the role of these molecules in the reorientation process is not yet defined. Here we...

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Detalhes bibliográficos
Main Authors: Andrés-Delgado, Laura, Antón, Olga M., Bartolini, Francesca, Ruiz-Sáenz, Ana, Correas, Isabel, Gundersen, Gregg G., Alonso, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444772/
https://ncbi.nlm.nih.gov/pubmed/22986496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201202137
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