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Adenovirus-mediated delivery of soluble ST2 attenuates ovalbumin-induced allergic asthma in mice

Allergic asthma is associated with excessive T helper type 2 (Th2) cells activation and airway hyperreactivity (AHR), implicated in the context of significant morbidity and mortality. Soluble ST2, a member of the interleukin (IL)-1 receptor family, has been shown to play a critical role in modulatio...

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Bibliographic Details
Main Authors: Yin, H, Li, X Y, Liu, T, Yuan, B H, Zhang, B B, Hu, S L, Gu, H B, Jin, X B, Zhu, J Y
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444711/
https://ncbi.nlm.nih.gov/pubmed/22943195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04629.x
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