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RNA plasticity and selectivity applicable to therapeutics and novel biosensor development

Aptamers are short, single-stranded nucleic acid sequences that are selected in vitro from large oligonucleotide libraries based on their high affinity to a target molecule. Hence, aptamers can be thought of as a nucleic acid analog to antibodies. However, several viewpoints hold that the potential...

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Detalhes bibliográficos
Main Authors: Nakamura, Yoshikazu, Ishiguro, Akira, Miyakawa, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444689/
https://ncbi.nlm.nih.gov/pubmed/22487172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2443.2012.01596.x
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