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Nutrient-Dependent Requirement for SOD1 in Lifespan Extension by Protein Restriction in Drosophila melanogaster

Reactive oxygen species (ROS) modulate aging and aging-related diseases. Dietary composition is critical in modulating lifespan. However, how ROS modulate dietary effects on lifespan remains poorly understood. Superoxide dismutase 1 (SOD1) is a major cytosolic enzyme responsible for scavenging super...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Xiaoping, Komatsu, Toshimitsu, Lim, Jinhwan, Laslo, Mara, Yolitz, Jason, Wang, Cecilia, Poirier, Luc, Alberico, Thomas, Zou, Sige
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444681/
https://ncbi.nlm.nih.gov/pubmed/22672579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00842.x
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