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The Impact of Aging on Mitochondrial Function and Biogenesis Pathways in Skeletal Muscle of Sedentary High- and Low-Functioning Elderly Individuals

Age-related loss of muscle mass and strength (sarcopenia) leads to a decline in physical function and frailty in the elderly. Among the many proposed underlying causes of sarcopenia, mitochondrial dysfunction is inherent in a variety of aged tissues. The intent of this study was to examine the effec...

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Detalhes bibliográficos
Main Authors: Joseph, Anna-Maria, Adhihetty, Peter J., Buford, Thomas W., Wohlgemuth, Stephanie E., Lees, Hazel A., Nguyen, Linda M.-D., Aranda, Juan M., Sandesara, Bhanu D., Pahor, Marco, Manini, Todd M., Marzetti, Emanuele, Leeuwenburgh, Christiaan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444680/
https://ncbi.nlm.nih.gov/pubmed/22681576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00844.x
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