Mitofusin 2-containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses via Inter-Organelle Ca(2+) Crosstalk

RATIONALE: Mitochondrial Ca(2+) uptake is essential for the bioenergetic feedback response through stimulation of Krebs cycle dehydrogenases. Close association of mitochondria to the sarcoplasmic reticulum (SR) may explain efficient mitochondrial Ca(2+) uptake despite low Ca(2+) affinity of the mito...

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Autori principali: Chen, Yun, Csordás, György, Jowdy, Casey, Schneider, Timothy G., Csordás, Norbert, Wang, Wei, Liu, Yingqiu, Kohlhaas, Michael, Meiser, Maxie, Bergem, Stefanie, Nerbonne, Jeanne M., Dorn, Gerald W., Maack, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444672/
https://ncbi.nlm.nih.gov/pubmed/22777004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.266585
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