Reduced BMP Signaling Results in Hindlimb Fusion with Lethal Pelvic/Urogenital Organ Aplasia: A New Mouse Model of Sirenomelia

Sirenomelia, also known as mermaid syndrome, is a developmental malformation of the caudal body characterized by leg fusion and associated anomalies of pelvic/urogenital organs including bladder, kidney, rectum and external genitalia. Most affected infants are stillborn, and the few born alive rarel...

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Detalhes bibliográficos
Main Authors: Suzuki, Kentaro, Adachi, Yasuha, Numata, Tomokazu, Nakada, Shoko, Yanagita, Motoko, Nakagata, Naomi, Evans, Sylvia M., Graf, Daniel, Economides, Aris, Haraguchi, Ryuma, Moon, Anne M., Yamada, Gen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444444/
https://ncbi.nlm.nih.gov/pubmed/23028455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043453
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