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Differential Impact of MexB Mutations on Substrate Selectivity of the MexAB-OprM Multidrug Efflux Pump of Pseudomonas aeruginosa

The integral inner membrane resistance-nodulation-division (RND) components of three-component RND-membrane fusion protein-outer membrane factor multidrug efflux systems define the substrate selectivity of these efflux systems. To gain a better understanding of what regions of these proteins are imp...

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Détails bibliographiques
Auteurs principaux: Middlemiss, Jocelyn K., Poole, Keith
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC344428/
https://ncbi.nlm.nih.gov/pubmed/14973037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.5.1258-1269.2004
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