ΔNp63 versatilely regulates a broad NF-κB gene program and promotes squamous epithelial proliferation, migration and inflammation

Head and neck squamous cell carcinoma (HNSCC) and many epithelial malignancies exhibit increased proliferation, invasion and inflammation, concomitant with aberrant nuclear activation of TP53 and NF-κB family members ΔNp63, c-REL and RELA. However, the mechanisms of crosstalk by which these transcri...

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Библиографические подробности
Главные авторы: Yang, Xinping, Lu, Hai, Yan, Bin, Romano, Rose-Anne, Bian, Yansong, Friedman, Jay, Duggal, Praveen, Allen, Clint, Chuang, Ryan, Ehsanian, Reza, Si, Han, Sinha, Satrajit, Van Waes, Carter, Chen, Zhong
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443863/
https://ncbi.nlm.nih.gov/pubmed/21576089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3445
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