Corticosteroid-modulated Immune Activation in the Tuberculosis Immune Reconstitution Inflammatory Syndrome

Rationale: HIV–tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an immunopathological reaction to mycobacterial antigens induced by antiretroviral therapy. Prednisone reduces morbidity in TB-IRIS, but the mechanisms are unclear. Objectives: To determine the effect of...

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Main Authors: Meintjes, Graeme, Skolimowska, Keira H., Wilkinson, Katalin A., Matthews, Kerryn, Tadokera, Rebecca, Conesa-Botella, Anali, Seldon, Ronnett, Rangaka, Molebogeng X., Rebe, Kevin, Pepper, Dominique J., Morroni, Chelsea, Colebunders, Robert, Maartens, Gary, Wilkinson, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443811/
https://ncbi.nlm.nih.gov/pubmed/22700860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201201-0094OC
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