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Nanoscale Electrostatic Domains in Cholesterol-Laden Lipid Membranes Create a Target for Amyloid Binding

Amyloid fibrils are associated with multiple neurodegenerative disorders, such as Alzheimer’s disease. Although biological membranes are involved in fibril plaque formation, the role of lipid membrane composition in fibril formation and toxicity is not well understood. We investigated the effect of...

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Detalhes bibliográficos
Main Authors: Drolle, Elizabeth, Gaikwad, Ravi M., Leonenko, Zoya
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443788/
https://ncbi.nlm.nih.gov/pubmed/22947946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.053
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