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Nanoscale Electrostatic Domains in Cholesterol-Laden Lipid Membranes Create a Target for Amyloid Binding
Amyloid fibrils are associated with multiple neurodegenerative disorders, such as Alzheimer’s disease. Although biological membranes are involved in fibril plaque formation, the role of lipid membrane composition in fibril formation and toxicity is not well understood. We investigated the effect of...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443788/ https://ncbi.nlm.nih.gov/pubmed/22947946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.053 |
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