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Direct observation of DNA distortion by the RSC chromatin remodelling complex

The Snf2 family represents a functionally diverse class of ATPase sharing the ability to modify DNA structure. Here we use a magnetic trap and an Atomic Force Microscope to monitor the activity of a member of this class: the RSC complex. This enzyme causes transient shortenings in DNA length involvi...

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Detalhes bibliográficos
Principais autores: Lia, Giuseppe, Praly, Elise, Ferreira, Helder, Stockdale, Chris, Tse-Dinh, Yuk Ching, Dunlap, David, Croquette, Vincent, Bensimon, David, Owen-Hughes, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443744/
https://ncbi.nlm.nih.gov/pubmed/16455496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2005.12.013
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