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Alternative pathways of disulfide bond formation yield secretion-competent, stable and functional immunoglobulins
Disulfide bonds within and between proteins are responsible for stabilizing folding and covalent assembly. They are thought to form by an obligatory pathway that leads to a single native structure compatible with secretion. We have previously demonstrated that the intradomain disulfide in the C(H)1...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443589/ https://ncbi.nlm.nih.gov/pubmed/18692901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.07.005 |
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