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A simplified method for study of RNA conformation - reaction of formylmethionine transfer RNA with [(14)C]methylamine-bisulfite

A new chemical method for radioactive labeling of single-stranded regions of RNA has been used to probe the three-dimensional structure of E. coli tRNA(fMet) in solution. The procedure involves conversion of cytosine residues to N(4)-[(14)C]methylcytosines by treatment with (14)CH(3)NH(2) and sodium...

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Bibliographic Details
Main Authors: Schulman, LaDonne H., Shapiro, Robert, Law, David C.F., Louis, Judith B.
Format: Artigo
Language:Inglês
Published: 1974
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC344352/
https://ncbi.nlm.nih.gov/pubmed/10793691
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