hESC-Derived Cardiomyocytes Electrically Couple and Suppress Arrhythmias in Injured Hearts

Transplantation studies in mice and rats have shown that human embryonic stem cell-derived cardiomyocytes (hESC-CMs) can improve the function of infarcted hearts(1–3), but two critical issues related to their electrophysiological behavior in vivo remain unresolved. First, the risk of arrhythmias fol...

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Detalhes bibliográficos
Main Authors: Shiba, Yuji, Fernandes, Sarah, Zhu, Wei-Zhong, Filice, Dominic, Muskheli, Veronica, Kim, Jonathan, Palpant, Nathan J., Gantz, Jay, Moyes, Kara White, Reinecke, Hans, Van Biber, Benjamin, Dardas, Todd, Mignone, John L., Izawa, Atsushi, Hanna, Ramy, Viswanathan, Mohan, Gold, Joseph D., Kotlikoff, Michael I., Sarvazyan, Narine, Kay, Matthew W., Murry, Charles E., Laflamme, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443324/
https://ncbi.nlm.nih.gov/pubmed/22864415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11317
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