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Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein

Parkinson’s disease (PD) is characterized by widespread alpha-synuclein pathology and neuronal loss, primarily of the nigrostriatal dopaminergic neurons. Inflammation has been implicated in PD, and alpha-synuclein can initiate microglial activation; however, the kinetics and distribution of inflamma...

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Bibliografische gegevens
Hoofdauteurs: Watson, Melanie B., Richter, Franziska, Lee, Soo Kyung, Gabby, Lauryn, Wu, Jennifer, Masliah, Eliezer, Effros, Rita B., Chesselet, Marie-Françoise
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443323/
https://ncbi.nlm.nih.gov/pubmed/22750327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.06.025
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